Correction of hair shaft defects through allele-specific silencing of mutant Krt75

Dominant mutations in keratin genes can cause a number of inheritable skin disorders characterized by intraepidermal blistering, epidermal hyperkeratosis, or abnormalities in skin appendages, such as nail plate dystrophy and structural defects in hair. Allele-specific silencing of mutant keratins th...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ying, Snedecor, Elizabeth R., Zhang, Xu, Xu, Yan-Feng, Huang, Lan, Jones, Evan, Zhang, Lianfeng, Clark, Richard A., Roop, Dennis R., Qin, Chuan, Chen, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764097/
https://www.ncbi.nlm.nih.gov/pubmed/26763422
http://dx.doi.org/10.1038/JID.2015.375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764097/
https://www.ncbi.nlm.nih.gov/pubmed/26763422
http://dx.doi.org/10.1038/JID.2015.375

Ejemplares similares