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Correction of hair shaft defects through allele-specific silencing of mutant Krt75
Dominant mutations in keratin genes can cause a number of inheritable skin disorders characterized by intraepidermal blistering, epidermal hyperkeratosis, or abnormalities in skin appendages, such as nail plate dystrophy and structural defects in hair. Allele-specific silencing of mutant keratins th...
Autores principales: | Liu, Ying, Snedecor, Elizabeth R., Zhang, Xu, Xu, Yan-Feng, Huang, Lan, Jones, Evan, Zhang, Lianfeng, Clark, Richard A., Roop, Dennis R., Qin, Chuan, Chen, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764097/ https://www.ncbi.nlm.nih.gov/pubmed/26763422 http://dx.doi.org/10.1038/JID.2015.375 |
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