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AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease

The adenosine monophosphate activated kinase protein (AMPK) is an evolutionary-conserved protein important for cell survival and organismal longevity through the modulation of energy homeostasis. Several studies suggested that AMPK activation may improve energy metabolism and protein clearance in th...

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Detalles Bibliográficos
Autores principales: Vázquez-Manrique, Rafael P., Farina, Francesca, Cambon, Karine, Dolores Sequedo, María, Parker, Alex J., Millán, José María, Weiss, Andreas, Déglon, Nicole, Neri, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764188/
https://www.ncbi.nlm.nih.gov/pubmed/26681807
http://dx.doi.org/10.1093/hmg/ddv513