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AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease
The adenosine monophosphate activated kinase protein (AMPK) is an evolutionary-conserved protein important for cell survival and organismal longevity through the modulation of energy homeostasis. Several studies suggested that AMPK activation may improve energy metabolism and protein clearance in th...
Autores principales: | Vázquez-Manrique, Rafael P., Farina, Francesca, Cambon, Karine, Dolores Sequedo, María, Parker, Alex J., Millán, José María, Weiss, Andreas, Déglon, Nicole, Neri, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764188/ https://www.ncbi.nlm.nih.gov/pubmed/26681807 http://dx.doi.org/10.1093/hmg/ddv513 |
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