Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms

Mutations in the ALS2 gene result in early-onset amyotrophic lateral sclerosis, infantile-onset ascending hereditary spastic paraplegia and juvenile primary lateral sclerosis, suggesting prominent upper motor neuron involvement. However, the importance of alsin function for corticospinal motor neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Gautam, Mukesh, Jara, Javier H., Sekerkova, Gabriella, Yasvoina, Marina V., Martina, Marco, Özdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764190/
https://www.ncbi.nlm.nih.gov/pubmed/26755825
http://dx.doi.org/10.1093/hmg/ddv631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764190/
https://www.ncbi.nlm.nih.gov/pubmed/26755825
http://dx.doi.org/10.1093/hmg/ddv631

Ejemplares similares