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2D Representation of Transcriptomes by t-SNE Exposes Relatedness between Human Tissues

The GTEx Consortium reported that hierarchical clustering of RNA profiles from 25 unique tissue types among 1641 individuals accurately distinguished the tissue types, but a multidimensional scaling failed to generate a 2D projection of the data that separates tissue-subtypes. In this study we show...

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Detalles Bibliográficos
Autores principales: Taskesen, Erdogan, Reinders, Marcel J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764374/
https://www.ncbi.nlm.nih.gov/pubmed/26906061
http://dx.doi.org/10.1371/journal.pone.0149853