Cargando…

Tunable protein synthesis by transcript isoforms in human cells

Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile...

Descripción completa

Detalles Bibliográficos
Autores principales: Floor, Stephen N, Doudna, Jennifer A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764583/
https://www.ncbi.nlm.nih.gov/pubmed/26735365
http://dx.doi.org/10.7554/eLife.10921