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Tunable protein synthesis by transcript isoforms in human cells
Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile...
Autores principales: | Floor, Stephen N, Doudna, Jennifer A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764583/ https://www.ncbi.nlm.nih.gov/pubmed/26735365 http://dx.doi.org/10.7554/eLife.10921 |
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