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Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis

A serious adverse clinical effect of glucocorticoid steroid treatment is secondary osteoporosis, enhancing fracture risk in bone. This rapid increase in bone fracture risk is largely independent of bone loss (quantity), and must therefore arise from degradation of the quality of the bone matrix at t...

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Detalles Bibliográficos
Autores principales: Karunaratne, A., Xi, L., Bentley, L., Sykes, D., Boyde, A., Esapa, C.T., Terrill, N.J., Brown, S.D.M., Cox, R.D., Thakker, R.V., Gupta, H.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764652/
https://www.ncbi.nlm.nih.gov/pubmed/26657825
http://dx.doi.org/10.1016/j.bone.2015.11.019