Cargando…
Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis
A serious adverse clinical effect of glucocorticoid steroid treatment is secondary osteoporosis, enhancing fracture risk in bone. This rapid increase in bone fracture risk is largely independent of bone loss (quantity), and must therefore arise from degradation of the quality of the bone matrix at t...
Autores principales: | Karunaratne, A., Xi, L., Bentley, L., Sykes, D., Boyde, A., Esapa, C.T., Terrill, N.J., Brown, S.D.M., Cox, R.D., Thakker, R.V., Gupta, H.S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764652/ https://www.ncbi.nlm.nih.gov/pubmed/26657825 http://dx.doi.org/10.1016/j.bone.2015.11.019 |
Ejemplares similares
-
Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development()()
por: Karunaratne, A., et al.
Publicado: (2012) -
Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality
por: Xi, L., et al.
Publicado: (2018) -
Genetic variation in WNT16 and its association with bone mineral density, fractures and osteoporosis in children with bone fragility()
por: Mäkitie, R.E., et al.
Publicado: (2022) -
Diagnostic yield of bone fragility gene panel sequencing in children and young adults referred for idiopathic primary osteoporosis at a single regional reference centre
por: Rouleau, Coline, et al.
Publicado: (2022) -
Guidelines for the management of osteoporosis and fragility fractures
por: Nuti, Ranuccio, et al.
Publicado: (2018)