Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis

The activation and transdifferentiation of hepatic stellate cells (HSCs) into contractile, matrix-producing myofibroblasts (MFBs) are central events in hepatic fibrogenesis. These processes are driven by autocrine- and paracrine-acting soluble factors (i.e., cytokines and chemokines). Proof-of-conce...

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Detalles Bibliográficos
Autores principales: Schon, Hans-Theo, Bartneck, Matthias, Borkham-Kamphorst, Erawan, Nattermann, Jacob, Lammers, Twan, Tacke, Frank, Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764688/
https://www.ncbi.nlm.nih.gov/pubmed/26941644
http://dx.doi.org/10.3389/fphar.2016.00033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764688/
https://www.ncbi.nlm.nih.gov/pubmed/26941644
http://dx.doi.org/10.3389/fphar.2016.00033

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