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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model

Background. Diabetic kidney disease is the leading cause of end-stage renal failure despite intensive treatment of modifiable risk factors. Identification of new drug targets is therefore of paramount importance. The complement system is emerging as a potential new target. The lectin pathway of the...

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Detalles Bibliográficos
Autores principales: Østergaard, Jakob Appel, Ruseva, Marieta Milkova, Malik, Talat Habib, Hoffmann-Petersen, Ingeborg Torp, Pickering, Matthew Caleb, Thiel, Steffen, Hansen, Troels Krarup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764751/
https://www.ncbi.nlm.nih.gov/pubmed/26977416
http://dx.doi.org/10.1155/2016/1825738