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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model
Background. Diabetic kidney disease is the leading cause of end-stage renal failure despite intensive treatment of modifiable risk factors. Identification of new drug targets is therefore of paramount importance. The complement system is emerging as a potential new target. The lectin pathway of the...
Autores principales: | Østergaard, Jakob Appel, Ruseva, Marieta Milkova, Malik, Talat Habib, Hoffmann-Petersen, Ingeborg Torp, Pickering, Matthew Caleb, Thiel, Steffen, Hansen, Troels Krarup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764751/ https://www.ncbi.nlm.nih.gov/pubmed/26977416 http://dx.doi.org/10.1155/2016/1825738 |
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