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Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development

Formalin-fixed, paraffin-embedded (FFPE) tissues are an underused resource for molecular analyses. This proof of concept study aimed to compare RNAseq results from FFPE biopsies with the corresponding RNAlater(®) (Qiagen, Germany) stored samples from clear cell renal cell carcinoma (ccRCC) patients...

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Detalles Bibliográficos
Autores principales: Eikrem, Oystein, Beisland, Christian, Hjelle, Karin, Flatberg, Arnar, Scherer, Andreas, Landolt, Lea, Skogstrand, Trude, Leh, Sabine, Beisvag, Vidar, Marti, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764764/
https://www.ncbi.nlm.nih.gov/pubmed/26901863
http://dx.doi.org/10.1371/journal.pone.0149743