Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis

There is increasing evidence that the Myocardin-related transcription factor/Serum response factor (MRTF/SRF) pathway plays a key role in fibroblast activation and that knocking down MRTF can lead to reduced scarring and fibrosis. Here, we have developed a receptor-targeted liposome-peptide-siRNA na...

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Detalles Bibliográficos
Autores principales: Yu-Wai-Man, Cynthia, Tagalakis, Aristides D., Manunta, Maria D., Hart, Stephen L., Khaw, Peng T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764806/
https://www.ncbi.nlm.nih.gov/pubmed/26905457
http://dx.doi.org/10.1038/srep21881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764806/
https://www.ncbi.nlm.nih.gov/pubmed/26905457
http://dx.doi.org/10.1038/srep21881

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