Systematic Evolution and Study of UAGN Decoding tRNAs in a Genomically Recoded Bacteria

We report the first systematic evolution and study of tRNA variants that are able to read a set of UAGN (N = A, G, U, C) codons in a genomically recoded E. coli strain that lacks any endogenous in-frame UAGN sequences and release factor 1. Through randomizing bases in anticodon stem-loop followed by...

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Detalles Bibliográficos
Autores principales: Wang, Nanxi, Shang, Xin, Cerny, Ronald, Niu, Wei, Guo, Jiantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764823/
https://www.ncbi.nlm.nih.gov/pubmed/26906548
http://dx.doi.org/10.1038/srep21898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764823/
https://www.ncbi.nlm.nih.gov/pubmed/26906548
http://dx.doi.org/10.1038/srep21898

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