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Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis

Lack of effective anti-metastatic drugs creates a major hurdle for metastatic lung cancer therapy. For successful lung cancer treatment, there is a strong need of newer therapeutics with metastasis-inhibitory potential. In the present study, we determined the anti-metastatic and anti-angiogenic pote...

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Detalles Bibliográficos
Autores principales: Shukla, Samriddhi, Sinha, Sonam, Khan, Sajid, Kumar, Sudhir, Singh, Kavita, Mitra, Kalyan, Maurya, Rakesh, Meeran, Syed Musthapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764833/
https://www.ncbi.nlm.nih.gov/pubmed/26905250
http://dx.doi.org/10.1038/srep21860