Unique Loss of the PYHIN Gene Family in Bats Amongst Mammals: Implications for Inflammasome Sensing

Recent genomic analysis of two bat species (Pteropus alecto and Myotis davidii) revealed the absence of the PYHIN gene family. This family is recognized as important immune sensors of intracellular self and foreign DNA and activators of the inflammasome and/or interferon pathways. Further assessment...

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Detalles Bibliográficos
Autores principales: Ahn, Matae, Cui, Jie, Irving, Aaron T., Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764838/
https://www.ncbi.nlm.nih.gov/pubmed/26906452
http://dx.doi.org/10.1038/srep21722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764838/
https://www.ncbi.nlm.nih.gov/pubmed/26906452
http://dx.doi.org/10.1038/srep21722

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