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Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury

Although protein-folding stress at the endoplasmic reticulum (ER) is emerging as a driver of neuronal dysfunction in models of spinal cord injury and neurodegeneration, the contribution of this pathway to peripheral nerve damage remains poorly explored. Here we targeted the unfolded protein response...

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Detalles Bibliográficos
Autores principales: Oñate, Maritza, Catenaccio, Alejandra, Martínez, Gabriela, Armentano, Donna, Parsons, Geoffrey, Kerr, Bredford, Hetz, Claudio, Court, Felipe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764858/
https://www.ncbi.nlm.nih.gov/pubmed/26906090
http://dx.doi.org/10.1038/srep21709