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Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

Glioma tumour-initiating cells (GTICs) can originate upon the transformation of neural progenitor cells (NPCs). Studies on GTICs have focused on primary tumours from which GTICs could be isolated and the use of human embryonic material. Recently, the somatic genomic landscape of human gliomas has be...

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Detalles Bibliográficos
Autores principales: Sancho-Martinez, Ignacio, Nivet, Emmanuel, Xia, Yun, Hishida, Tomoaki, Aguirre, Aitor, Ocampo, Alejandro, Ma, Li, Morey, Robert, Krause, Marie N., Zembrzycki, Andreas, Ansorge, Olaf, Vazquez-Ferrer, Eric, Dubova, Ilir, Reddy, Pradeep, Lam, David, Hishida, Yuriko, Wu, Min-Zu, Esteban, Concepcion Rodriguez, O'Leary, Dennis, Wahl, Geoffrey M., Verma, Inder M., Laurent, Louise C., Izpisua Belmonte, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764898/
https://www.ncbi.nlm.nih.gov/pubmed/26899176
http://dx.doi.org/10.1038/ncomms10743