Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation

Tissue fibrosis contributes to nearly half of all deaths in the developed world and is characterized by progressive matrix stiffening. Despite this, nearly all in vitro disease models are mechanically static. Here, we used visible light-mediated stiffening hydrogels to investigate cell mechanotransd...

Descripción completa

Detalles Bibliográficos
Autores principales: Caliari, Steven R., Perepelyuk, Maryna, Cosgrove, Brian D., Tsai, Shannon J., Lee, Gi Yun, Mauck, Robert L., Wells, Rebecca G., Burdick, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764908/
https://www.ncbi.nlm.nih.gov/pubmed/26906177
http://dx.doi.org/10.1038/srep21387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764908/
https://www.ncbi.nlm.nih.gov/pubmed/26906177
http://dx.doi.org/10.1038/srep21387

Ejemplares similares