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Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization
Antibodies are essential for structural determinations and functional studies of membrane proteins, but antibody generation is limited by the availability of properly-folded and purified antigen. We describe the first application of genetic immunization to a structurally diverse set of membrane prot...
Autores principales: | Hansen, Debra T., Robida, Mark D., Craciunescu, Felicia M., Loskutov, Andrey V., Dörner, Katerina, Rodenberry, John-Charles, Wang, Xiao, Olson, Tien L., Patel, Hetal, Fromme, Petra, Sykes, Kathryn F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764931/ https://www.ncbi.nlm.nih.gov/pubmed/26908053 http://dx.doi.org/10.1038/srep21925 |
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