Impaired theta-gamma coupling in APP-deficient mice

Amyloid precursor protein (APP) is critically involved in the pathophysiology of Alzheimer’s disease, but its physiological functions remain elusive. Importantly, APP knockout (APP-KO) mice exhibit cognitive deficits, suggesting that APP plays a role at the neuronal network level. To investigate thi...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomin, Zhong, Wewei, Brankačk, Jurij, Weyer, Sascha W., Müller, Ulrike C., Tort, Adriano B. L., Draguhn, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764939/
https://www.ncbi.nlm.nih.gov/pubmed/26905287
http://dx.doi.org/10.1038/srep21948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764939/
https://www.ncbi.nlm.nih.gov/pubmed/26905287
http://dx.doi.org/10.1038/srep21948

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