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Insights into the mechanism of human papillomavirus E2-induced procaspase-8 activation and cell death

High-risk human papillomavirus (HR-HPV) E2 protein, the master regulator of viral life cycle, induces apoptosis of host cell that is independent of its virus-associated regulatory functions. E2 protein of HR-HPV18 has been found to be involved in novel FADD-independent activation of caspase-8, howev...

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Detalles Bibliográficos
Autores principales: Singh, Nitu, Senapati, Sanjib, Bose, Kakoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764946/
https://www.ncbi.nlm.nih.gov/pubmed/26906543
http://dx.doi.org/10.1038/srep21408