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Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression

Plasma advanced oxidation protein products (AOPPs), a class of pro-inflammatory pathogenic mediators, accumulate in subjects with chronic kidney disease. Whether AOPPs contribute to coagulation abnormalities, which are frequently seen in uremic patients, is unknown. Here we report that AOPPs activat...

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Detalles Bibliográficos
Autores principales: Pasterk, Lisa, Lemesch, Sandra, Leber, Bettina, Trieb, Markus, Curcic, Sanja, Stadlbauer, Vanessa, Schuligoi, Rufina, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764952/
https://www.ncbi.nlm.nih.gov/pubmed/26905525
http://dx.doi.org/10.1038/srep22104