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Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms

The CRISPR-Cas system of prokaryotic adaptive immunity displays features of a mechanism for directional, Lamarckian evolution. Indeed, this system modifies a specific locus in a bacterial or archaeal genome by inserting a piece of foreign DNA into a CRISPR array which results in acquired, heritable...

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Detalles Bibliográficos
Autores principales: Koonin, Eugene V., Wolf, Yuri I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765028/
https://www.ncbi.nlm.nih.gov/pubmed/26912144
http://dx.doi.org/10.1186/s13062-016-0111-z