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Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms
The CRISPR-Cas system of prokaryotic adaptive immunity displays features of a mechanism for directional, Lamarckian evolution. Indeed, this system modifies a specific locus in a bacterial or archaeal genome by inserting a piece of foreign DNA into a CRISPR array which results in acquired, heritable...
Autores principales: | Koonin, Eugene V., Wolf, Yuri I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765028/ https://www.ncbi.nlm.nih.gov/pubmed/26912144 http://dx.doi.org/10.1186/s13062-016-0111-z |
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