Systematic evaluation of the impact of ChIP-seq read designs on genome coverage, peak identification, and allele-specific binding detection

BACKGROUND: Chromatin immunoprecipitation followed by sequencing (ChIP-seq) experiments revolutionized genome-wide profiling of transcription factors and histone modifications. Although maturing sequencing technologies allow these experiments to be carried out with short (36–50 bps), long (75–100 bp...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Zeng, Xin, Younkin, Sam, Kawli, Trupti, Snyder, Michael P., Keleş, Sündüz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765064/
https://www.ncbi.nlm.nih.gov/pubmed/26908256
http://dx.doi.org/10.1186/s12859-016-0957-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765064/
https://www.ncbi.nlm.nih.gov/pubmed/26908256
http://dx.doi.org/10.1186/s12859-016-0957-1

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