Simultaneous quantification of artesunate and mefloquine in fixed-dose combination tablets by multivariate calibration with middle infrared spectroscopy and partial least squares regression

BACKGROUND: Malaria is one of the most lethal and life-threatening infectious diseases in the world, causing more than half a million deaths annually. Treatment with mefloquine and artesunate is currently recommended by the World Health Organization, and was historically the first artemisinin-based...

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Detalles Bibliográficos
Autores principales: Marson, Breno Maurício, de Oliveira Vilhena, Raquel, de Souza Madeira, Camilla Regina, Pontes, Flávia Lada Degaut, Piantavini, Mário Sérgio, Pontarolo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765072/
https://www.ncbi.nlm.nih.gov/pubmed/26911371
http://dx.doi.org/10.1186/s12936-016-1157-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765072/
https://www.ncbi.nlm.nih.gov/pubmed/26911371
http://dx.doi.org/10.1186/s12936-016-1157-1

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