Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells

BACKGROUND: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for therapeutic intervention. In the current study, we eva...

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Detalles Bibliográficos
Autores principales: Trisdale, Sarah K., Schwab, Nicolette M., Hou, Xiaoying, Davis, John S., Townson, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765146/
https://www.ncbi.nlm.nih.gov/pubmed/26911253
http://dx.doi.org/10.1186/s13048-016-0217-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765146/
https://www.ncbi.nlm.nih.gov/pubmed/26911253
http://dx.doi.org/10.1186/s13048-016-0217-z

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