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Structure-based Markov random field model for representing evolutionary constraints on functional sites
BACKGROUND: Elucidating the cooperative mechanism of interconnected residues is an important component toward understanding the biological function of a protein. Coevolution analysis has been developed to model the coevolutionary information reflecting structural and functional constraints. Recently...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765150/ https://www.ncbi.nlm.nih.gov/pubmed/26911566 http://dx.doi.org/10.1186/s12859-016-0948-2 |