Cargando…

Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs

BACKGROUND: Cancer stem cells (CSCs) have been invoked in resistance, recurrence and metastasis of cancer. Consequently, curative cancer treatments may be contingent on CSC selective approaches. Of particular interest in this respect is the ionophore salinomycin, a natural product shown to be 100-fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xiaoli, Borgström, Björn, Kempengren, Sebastian, Persson, Lo, Hegardt, Cecilia, Strand, Daniel, Oredsson, Stina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765157/
https://www.ncbi.nlm.nih.gov/pubmed/26906175
http://dx.doi.org/10.1186/s12885-016-2142-3