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Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs
BACKGROUND: Cancer stem cells (CSCs) have been invoked in resistance, recurrence and metastasis of cancer. Consequently, curative cancer treatments may be contingent on CSC selective approaches. Of particular interest in this respect is the ionophore salinomycin, a natural product shown to be 100-fo...
Autores principales: | Huang, Xiaoli, Borgström, Björn, Kempengren, Sebastian, Persson, Lo, Hegardt, Cecilia, Strand, Daniel, Oredsson, Stina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765157/ https://www.ncbi.nlm.nih.gov/pubmed/26906175 http://dx.doi.org/10.1186/s12885-016-2142-3 |
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