The uncoupled ATPase activity of the ABC transporter BtuC(2)D(2) leads to a hysteretic conformational change, conformational memory, and improved activity

ABC transporters comprise a large and ubiquitous family of proteins. From bacteria to man they translocate solutes at the expense of ATP hydrolysis. Unlike other enzymes that use ATP as an energy source, ABC transporters are notorious for having high levels of basal ATPase activity: they hydrolyze A...

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Detalles Bibliográficos
Autores principales: Livnat-Levanon, Nurit, I. Gilson, Amy, Ben-Tal, Nir, Lewinson, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765350/
https://www.ncbi.nlm.nih.gov/pubmed/26905293
http://dx.doi.org/10.1038/srep21696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765350/
https://www.ncbi.nlm.nih.gov/pubmed/26905293
http://dx.doi.org/10.1038/srep21696

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