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The uncoupled ATPase activity of the ABC transporter BtuC(2)D(2) leads to a hysteretic conformational change, conformational memory, and improved activity
ABC transporters comprise a large and ubiquitous family of proteins. From bacteria to man they translocate solutes at the expense of ATP hydrolysis. Unlike other enzymes that use ATP as an energy source, ABC transporters are notorious for having high levels of basal ATPase activity: they hydrolyze A...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765350/ https://www.ncbi.nlm.nih.gov/pubmed/26905293 http://dx.doi.org/10.1038/srep21696 |