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Autoantibodies against the Second Extracellular Loop of M3R Do neither Induce nor Indicate Primary Sjögren’s Syndrome

OBJECTIVES: Anti-muscarinic acetylcholine type-3 receptor (anti-M3R) autoantibodies have been suggested to be pathogenic for primary Sjögren’s syndrome (pSS), and the second extracellular loop of M3R is suspected to carry a disease-promoting epitope. In this study, we aimed to evaluate the pathogeni...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Zheng, Junfeng, Huang, Qiaoniang, Deng, Fengyuan, Huang, Renliang, Zhao, Wenjie, Yin, Junping, Song, Lina, Chen, Juan, Gao, Xing, Liu, Zuguo, Petersen, Frank, Yu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765836/
https://www.ncbi.nlm.nih.gov/pubmed/26901532
http://dx.doi.org/10.1371/journal.pone.0149485