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Refined elasticity sampling for Monte Carlo-based identification of stabilizing network patterns

Motivation: Structural kinetic modelling (SKM) is a framework to analyse whether a metabolic steady state remains stable under perturbation, without requiring detailed knowledge about individual rate equations. It provides a representation of the system’s Jacobian matrix that depends solely on the n...

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Detalles Bibliográficos
Autores principales: Childs, Dorothee, Grimbs, Sergio, Selbig, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765856/
https://www.ncbi.nlm.nih.gov/pubmed/26072485
http://dx.doi.org/10.1093/bioinformatics/btv243