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Refined elasticity sampling for Monte Carlo-based identification of stabilizing network patterns
Motivation: Structural kinetic modelling (SKM) is a framework to analyse whether a metabolic steady state remains stable under perturbation, without requiring detailed knowledge about individual rate equations. It provides a representation of the system’s Jacobian matrix that depends solely on the n...
Autores principales: | Childs, Dorothee, Grimbs, Sergio, Selbig, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765856/ https://www.ncbi.nlm.nih.gov/pubmed/26072485 http://dx.doi.org/10.1093/bioinformatics/btv243 |
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