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Robust reconstruction of gene expression profiles from reporter gene data using linear inversion

Motivation: Time-series observations from reporter gene experiments are commonly used for inferring and analyzing dynamical models of regulatory networks. The robust estimation of promoter activities and protein concentrations from primary data is a difficult problem due to measurement noise and the...

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Detalles Bibliográficos
Autores principales: Zulkower, Valentin, Page, Michel, Ropers, Delphine, Geiselmann, Johannes, de Jong, Hidde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765859/
https://www.ncbi.nlm.nih.gov/pubmed/26072511
http://dx.doi.org/10.1093/bioinformatics/btv246