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cNMA: a framework of encounter complex-based normal mode analysis to model conformational changes in protein interactions

Motivation: It remains both a fundamental and practical challenge to understand and anticipate motions and conformational changes of proteins during their associations. Conventional normal mode analysis (NMA) based on anisotropic network model (ANM) addresses the challenge by generating normal modes...

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Detalles Bibliográficos
Autores principales: Oliwa, Tomasz, Shen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765865/
https://www.ncbi.nlm.nih.gov/pubmed/26072477
http://dx.doi.org/10.1093/bioinformatics/btv252