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cNMA: a framework of encounter complex-based normal mode analysis to model conformational changes in protein interactions
Motivation: It remains both a fundamental and practical challenge to understand and anticipate motions and conformational changes of proteins during their associations. Conventional normal mode analysis (NMA) based on anisotropic network model (ANM) addresses the challenge by generating normal modes...
Autores principales: | Oliwa, Tomasz, Shen, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765865/ https://www.ncbi.nlm.nih.gov/pubmed/26072477 http://dx.doi.org/10.1093/bioinformatics/btv252 |
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