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Chemoproteomic profiling of host and pathogen enzymes active in cholera

Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active in animals infected with the cholera pathogen Vibrio cholerae. Four V. cholerae protease...

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Detalles Bibliográficos
Autores principales: Hatzios, Stavroula K., Abel, Sören, Martell, Julianne, Hubbard, Troy, Sasabe, Jumpei, Munera, Diana, Clark, Lars, Bachovchin, Daniel A., Qadri, Firdausi, Ryan, Edward T., Davis, Brigid M., Weerapana, Eranthie, Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765928/
https://www.ncbi.nlm.nih.gov/pubmed/26900865
http://dx.doi.org/10.1038/nchembio.2025