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Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling

Neuronal senescence caused by diabetic neuropathy is considered a common complication of diabetes mellitus. Neuronal senescence leads to the secretion of pro-inflammatory cytokines, the production of reactive oxygen species, and the alteration of cellular homeostasis. Agmatine, which is biosynthesiz...

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Detalles Bibliográficos
Autores principales: Song, Juhyun, Lee, Byeori, Kang, Somang, Oh, Yumi, Kim, Eosu, Kim, Chul-Hoon, Song, Ho-Taek, Lee, Jong Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766111/
https://www.ncbi.nlm.nih.gov/pubmed/26924930
http://dx.doi.org/10.5607/en.2016.25.1.24