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Trials in adult critical care that show increased mortality of the new intervention: Inevitable or preventable mishaps?

Several promising therapies assessed in the adult critically ill in large, multicenter randomized controlled trials (RCTs) were associated with significantly increased mortality in the intervention arms. Our hypothesis was that there would be wide ranges in sponsorship (industry or not), type(s) of...

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Detalles Bibliográficos
Autores principales: Russell, James A., Williams, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766166/
https://www.ncbi.nlm.nih.gov/pubmed/26909519
http://dx.doi.org/10.1186/s13613-016-0120-1