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Simultaneous detection of lysine metabolites by a single LC–MS/MS method: monitoring lysine degradation in mouse plasma

Detection and quantification of lysine degradation metabolites in plasma is necessary for the diagnosis and follow-up of diseases such as pyridoxine-dependent epilepsy. The principal metabolites involved in the disease are related to the first steps of lysine oxidation, either through the saccharopi...

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Detalles Bibliográficos
Autores principales: Pena, Izabella A., Marques, Lygia A., Laranjeira, Angelo B. A., Yunes, José A., Eberlin, Marcos N., Arruda, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766172/
https://www.ncbi.nlm.nih.gov/pubmed/27026869
http://dx.doi.org/10.1186/s40064-016-1809-1