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Simultaneous detection of lysine metabolites by a single LC–MS/MS method: monitoring lysine degradation in mouse plasma
Detection and quantification of lysine degradation metabolites in plasma is necessary for the diagnosis and follow-up of diseases such as pyridoxine-dependent epilepsy. The principal metabolites involved in the disease are related to the first steps of lysine oxidation, either through the saccharopi...
Autores principales: | Pena, Izabella A., Marques, Lygia A., Laranjeira, Angelo B. A., Yunes, José A., Eberlin, Marcos N., Arruda, Paulo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766172/ https://www.ncbi.nlm.nih.gov/pubmed/27026869 http://dx.doi.org/10.1186/s40064-016-1809-1 |
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