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Effects of Megaplasmid Loss on Growth of Neurotoxigenic Clostridium butyricum Strains and Botulinum Neurotoxin Type E Expression

Clostridium butyricum strains that atypically produce the botulinum neurotoxin type E (BoNT/E) possess a megaplasmid of unknown functions in their genome. In this study, we cured two botulinum neurotoxigenic C. butyricum type E strains of their megaplasmids, and compared the obtained megaplasmid-cur...

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Detalles Bibliográficos
Autores principales: Scalfaro, Concetta, Iacobino, Angelo, Grande, Laura, Morabito, Stefano, Franciosa, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766289/
https://www.ncbi.nlm.nih.gov/pubmed/26941734
http://dx.doi.org/10.3389/fmicb.2016.00217