D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability

D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine. It is crucial for synaptic plasticity and is implicated in schizophrenia. Our previous studies demonstrated specific loss of SR, D-serine-r...

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Detalles Bibliográficos
Autores principales: Lin, Hong, Jacobi, Ariel A., Anderson, Stewart A., Lynch, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766304/
https://www.ncbi.nlm.nih.gov/pubmed/26941605
http://dx.doi.org/10.3389/fncel.2016.00034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766304/
https://www.ncbi.nlm.nih.gov/pubmed/26941605
http://dx.doi.org/10.3389/fncel.2016.00034

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