Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction o...

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Detalles Bibliográficos
Autores principales: Robinson, Prema, Kasembeli, Moses, Bharadwaj, Uddalak, Engineer, Nikita, Eckols, Kris T., Tweardy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766315/
https://www.ncbi.nlm.nih.gov/pubmed/26981525
http://dx.doi.org/10.1155/2016/1959270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766315/
https://www.ncbi.nlm.nih.gov/pubmed/26981525
http://dx.doi.org/10.1155/2016/1959270

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