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Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance
Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction o...
Autores principales: | Robinson, Prema, Kasembeli, Moses, Bharadwaj, Uddalak, Engineer, Nikita, Eckols, Kris T., Tweardy, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766315/ https://www.ncbi.nlm.nih.gov/pubmed/26981525 http://dx.doi.org/10.1155/2016/1959270 |
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